A study on effect of glycemic control on cardiac autonomic function tests in type 2 diabetes

Abstract

The present study was undertaken to estimate the glycosylated Hb level in type-2 diabetic subjects by cation-exchange- resin method and to study the relation between glycemic control and cardiac autonomic function. The study comprised of 90 subjects, 60 Diabetic mellitus type 2 patients and 30 age matched normal individuals. Diabetic mellitus type 2 patients were further classified in to two sub-groups, Type2 Diabetic mellitus patients with good glycemic control (HbA1c < 7) and Type2 Diabetic mellitus patients with poor glycemic control (HbA1c > 7). The basis of finding is multifactorial and may be at multiple levels of neuraxis including peripheral and central mechanisms as reviewed under pathophysiology of diabetic autonomic neuropathy.